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堪萨斯分枝杆菌所致非结核分枝杆菌肺部感染伴胸腔积液

[Nontuberculous Mycobacterium pulmonary infection with pleural effusion caused by Mycobacterium kansasii].

作者信息

Igari H, Kikuchi N

机构信息

Department of Internal Medicine, Chiba Kaihin Municipal Hospital, Japan.

出版信息

Kekkaku. 1993 Aug;68(8):527-31.

PMID:8377327
Abstract

A 28 year-old man was admitted to our hospital because of fever, cough and chest pain. A chest X-ray film taken on admission showed infiltrate in the left upper lung field with ipsilateral pleural effusion. Microscopical examinations of stained specimens of sputa and pleural effusions disclosed no acid-fast bacilli. The level of adenosine deaminase (ADA) in pleural effusion was 46.4 IU/l. A tuberculin skin test was moderately positive. The most probable diagnosis was pulmonary tuberculosis with pleural effusion. Isoniazid (INH) and rifampicin (RFP) were administered on the 5th hospital day and continued to lower the fever and reduce the pleural effusion. The cultured specimens of sputa and pleural effusions yielded Mycobacterium kansasii. After six months of treatment, chest X-ray film showed improvement and the administration of INH, RFP was discontinued without recurrence.

摘要

一名28岁男性因发热、咳嗽和胸痛入院。入院时拍摄的胸部X光片显示左上肺野浸润伴同侧胸腔积液。痰液和胸腔积液染色标本的显微镜检查未发现抗酸杆菌。胸腔积液中腺苷脱氨酶(ADA)水平为46.4 IU/l。结核菌素皮肤试验呈中度阳性。最可能的诊断是肺结核伴胸腔积液。在住院第5天给予异烟肼(INH)和利福平(RFP),持续用药后发热减退,胸腔积液减少。痰液和胸腔积液培养标本培养出堪萨斯分枝杆菌。经过6个月的治疗,胸部X光片显示病情改善,停用INH、RFP后未复发。

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