Kirchler H C, Seebacher S, Alge A A, Müller-Holzner E, Fessler S, Kölle D
Department of Obstetrics and Gynecology, University Hospital of Innsbruck, Austria.
Obstet Gynecol. 1993 Oct;82(4 Pt 1):561-5.
To improve the accuracy and speed of diagnosis of an ectopic tubal pregnancy by means of blood flow analysis in the tubal arteries. We hypothesized that invasion of the trophoblast increases blood flow in the tubal artery involved in ectopic pregnancy.
In 394 patients, using an endovaginal triplex color Doppler ultrasonography system, we performed qualitative blood flow analysis in the tubal arteries on both sides. The percentage of the between-side difference in tubal blood flow was calculated.
There was an increase in tubal blood flow on the ectopic pregnancy side, and the mean between-side difference in tubal blood flow was 20.45% in the ectopic pregnancy group. In the control groups, the between-side difference was 2.95% (t = 21.5, P < .00001). Using a cutoff point of 8% for the percentage of the between-side difference in tubal blood flow, the method had a sensitivity of 85% and a specificity of 96% for diagnosing an ectopic pregnancy. The percentage of the between-side difference in tubal blood flow was independent of gestational age (Pearson correlation coefficient 0.081).
The advantages of this new method for diagnosing tubal pregnancy are early detection, noninvasivity, and immediate results.
通过分析输卵管动脉血流来提高输卵管妊娠诊断的准确性和速度。我们假设滋养层细胞的侵入会增加宫外孕受累侧输卵管动脉的血流量。
对394例患者，使用经阴道三维彩色多普勒超声系统，对双侧输卵管动脉进行血流定性分析。计算双侧输卵管血流差异百分比。
宫外孕侧输卵管血流量增加，宫外孕组双侧输卵管血流平均差异为20.45%。在对照组中，双侧差异为2.95%（t = 21.5，P <.00001）。以输卵管血流双侧差异百分比8%为界值，该方法诊断宫外孕的敏感性为85%，特异性为96%。输卵管血流双侧差异百分比与孕周无关（Pearson相关系数0.081）。
这种诊断输卵管妊娠的新方法具有早期检测、无创和结果即时的优点。
