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[细菌黏附:上尿路感染中的毒力因子]

[Bacterial adherence: virulence factor in upper urinary tract infections].

作者信息

Archambaud M

机构信息

Laboratoire de bactériologie, CHU Rangueil, Toulouse.

出版信息

Rev Prat. 1993 May 1;43(9):1069-71.

PMID:8378713
Abstract

The possibility that have certain strains of Escherichia coli to adhere to the urinary epithelium, constitutes a real pathogenic character. This adhesivity is specific and occurs through proteic structures (adhesins), that are present on the surface of bacteria and which recognize complementary receptors on uroepithelial cells. Studies of the frequency of these adhesins in different types of urinary tract infections, as well as experimental studies in animals all point towards an important role played by adhesins in the pathogenesis of the upper urinary tract infection.

摘要

某些大肠杆菌菌株黏附于尿路上皮的可能性构成了一种真正的致病特性。这种黏附性具有特异性,通过蛋白质结构(黏附素)发生,黏附素存在于细菌表面,可识别尿路上皮细胞上的互补受体。对不同类型尿路感染中这些黏附素频率的研究以及在动物身上进行的实验研究均表明,黏附素在上尿路感染的发病机制中发挥着重要作用。

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