Deviatov A S, Kalashnikov S A, Prokof'ev E M
Vestn Khir Im I I Grek. 1993 Mar-Apr;150(3-4):51-3.
The work describes results of the application of a new highly effective hemostatic drug--Caprofer. The investigations were performed in 61 rabbits who were given graded injuries of the liver, kidney and spleen. In all the cases hemostasis made its appearance quickly within 1-20 sec. after the application of Caprofer. Reliability of hemostasis was checked by the method of hydropressure of the organs under study which was shown to be very high. Caprofer was used under clinical conditions in 61 patients in operations for traumas and diseases of the liver, kidney, spleen, gallbladder and in resection of the prostate. The results obtained speak of high efficiency of Caprofer for parenchymatous bleedings. Pronounced adhesive properties of the drug were noted as well as the absence of undesirable side effects.
该研究描述了一种新型高效止血药物——卡普罗芬(Caprofer)的应用结果。研究对61只家兔进行了实验,分别对其肝脏、肾脏和脾脏造成不同程度的损伤。在所有情况下,应用卡普罗芬后1至20秒内止血迅速出现。通过对所研究器官进行水压测试的方法检查止血的可靠性,结果显示该可靠性非常高。卡普罗芬在临床条件下应用于61例因肝脏、肾脏、脾脏、胆囊创伤和疾病以及前列腺切除术的患者。所获得的结果表明卡普罗芬对实质性出血具有高效性。还注意到该药物具有显著的黏附特性,且无不良副作用。