Späth-Schwalbe E, Preclik G, Heimpel H
Abteilung Innere Medizin I und III, Universitätsklinik Ulm.
Z Gastroenterol. 1993 Jul-Aug;31(7-8):447-9.
A 75-year-old man with angiodysplasia of the sigmoid and rectum and recurrent lower gastrointestinal bleeding episodes, despite repeated endoscopic laser-coagulation, was successfully treated with oestrogen-progesterone. Besides angiodysplasia he had aortic valvular stenosis, monoclonal gammopathy, mild renal insufficiency, and moderate peripheral arteriosclerosis obliterans. Oestrogen-progesterone may be a valuable alternative therapy in elderly patients with repeated bleeding, despite endoscopic coagulation, secondary to gastrointestinal angiodysplasia which cannot be treated surgically, in patients who deny surgery, or with rebleeding after surgery.
一名75岁男性，患有乙状结肠和直肠血管发育异常，尽管反复进行内镜激光凝固治疗，仍反复出现下消化道出血，使用雌激素 - 孕激素治疗成功。除血管发育异常外，他还患有主动脉瓣狭窄、单克隆丙种球蛋白病、轻度肾功能不全和中度外周动脉硬化闭塞症。对于因胃肠道血管发育异常导致反复出血、尽管进行了内镜凝固治疗但无法手术治疗、拒绝手术或术后再出血的老年患者，雌激素 - 孕激素可能是一种有价值的替代治疗方法。
