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肠道慢性炎症性疾病中的泌尿系统并发症

Urological complications in chronic inflammatory diseases of the bowel.

作者信息

Sigel A, Botticher R, Wilhelm E

出版信息

Eur Urol. 1977;3(1):7-10. doi: 10.1159/000472046.

Abstract

In advanced stages, the three most common inflammatory bowel diseases - colonic diverticulitis, Crohn's disease and ulcerative colitis - cause, in some 10% of cases, secondary urological pathology involving either bladder or ureter. Colovesical fistula is found more frequently in diverticulitis and less often in Crohn's disease, which penetrates predominantly from the ileum into the bladder. On the other hand, if uretic stenosis develops it will be caused on the right side by Crohn's disease and on the left by ulcerative colitis. Vesico-intestinal fistulae will close without sequelae after resection of the diseased bowel segment. On the other hand, retroperitoneal ureteric stenosis - despite bowel resection and ureterolysis - will often require nephrectomy if operation is not carried out early enough. Frequent re-checks with infusion excretory urography will help to prevent this. Nephrolithiasis, amyloidosis and contracted bladder are other, though less common, complications of chronic inflammatory diseases of the bowel.

摘要

在疾病晚期,三种最常见的炎症性肠病——结肠憩室炎、克罗恩病和溃疡性结肠炎——在约10%的病例中会引发涉及膀胱或输尿管的继发性泌尿系统病变。结肠膀胱瘘在憩室炎中更为常见,在克罗恩病中较少见,克罗恩病主要从回肠穿入膀胱。另一方面,如果发生输尿管狭窄,右侧由克罗恩病引起,左侧由溃疡性结肠炎引起。病变肠段切除后,膀胱肠瘘会自愈且无后遗症。另一方面,腹膜后输尿管狭窄——尽管进行了肠切除和输尿管松解术——如果手术不够及时,往往需要进行肾切除术。频繁进行静脉肾盂造影复查有助于预防这种情况。肾结石、淀粉样变性和膀胱挛缩是肠道慢性炎症性疾病的其他并发症,不过相对少见。

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