Menzeleev R F, Smirnova G P, Chekareva N V, Zvonkova E N, Krasnopol'skiĭ Iu M, Shvets V I
Bioorg Khim. 1993 Aug;19(8):817-24.
An increase of the mouse fibroblast proliferation by ganglioside GM3 from equine erythrocytes is described. The structure of GM3 has been established on the basis of chemical methods, enzymatic degradation, GC-MS, as well as plasma desorption mass spectrometry and HPLC of 9-anthrylmethyl esters of gangliosides to characterize the long-chain base composition. The oligosaccharide moiety includes an N-glycolylneuraminic acid residue, whereas the main components of the lipid moiety are 20:1 sphingosine and 24:0 fatty acids.
本文描述了马红细胞神经节苷脂GM3可促进小鼠成纤维细胞增殖。GM3的结构已通过化学方法、酶降解、气相色谱-质谱联用、等离子体解吸质谱以及神经节苷脂9-蒽甲基酯的高效液相色谱法得以确定，以表征长链碱基组成。寡糖部分包含一个N-羟乙酰神经氨酸残基，而脂质部分的主要成分是20:1鞘氨醇和24:0脂肪酸。
