Suadicani P, Hein H O, Gyntelberg F
Epidemiological Research Unit, Rigshospitalet, State University Hospital, Copenhagen, Denmark.
Atherosclerosis. 1993 Jul;101(2):165-75. doi: 10.1016/0021-9150(93)90113-9.
Large social inequalities exist in the risk of ischaemic heart disease (IHD), and they are only partly explained by established cardiovascular disease risk factors. Social class differences in psychosocial working conditions could be important explanatory factors. In a cohort of 1752 employed males, age in years, mean (S.D.): 59.7 (3.5), we investigated the issue. Self-reported psychosocial working conditions examined were: influence on the job, work monotony, work pace, degree of satisfaction with immediate superiors and colleagues, and ability to relax after working hours. One hundred and fourteen men were excluded due to prevalent cardiovascular disease. During the follow-up period (1985/86-1989), 46 men (approx. 3%) suffered an IHD event, 11 events were fatal. Compared with the rest, the highest social class had a relative risk with 95% CI (RR) of IHD of 0.26 (0.06-1.09), an association which was not explained by major potentially confounding or effect modifying factors: smoking, alcohol, physical activity, blood pressure, hypertension, body mass index, serum cholesterol, serum triglycerides, serum HDL, and serum selenium. Including psychosocial factors in the multivariate model had little influence on the estimate, RR = 0.21 (0.05-0.95), and yet there were highly significant differences in psychosocial working conditions between social classes. Neither self-reported influence on the job, work monotony, work pace, degree of satisfaction with immediate superiors and colleagues, nor interactions of the above factors were significantly associated with risk of IHD. However, men who reported that they were incapable of relaxing after working hours had a highly significant approximately threefold increased risk of IHD. We conclude that in middle-aged and elderly males self-reported, i.e. subjective psychosocial working conditions, did not contribute to the explanation of social inequalities in IHD, and that self-reported incapability to relax after work was associated with an increased risk of IHD.
缺血性心脏病(IHD)风险存在巨大的社会不平等现象,而既定的心血管疾病风险因素只能部分解释这些不平等。心理社会工作条件方面的社会阶层差异可能是重要的解释因素。在一个由1752名在职男性组成的队列中,年龄以岁计,均值(标准差):59.7(3.5),我们对这一问题进行了调查。所考察的自我报告的心理社会工作条件包括:对工作的影响力、工作单调性、工作节奏、对直属上级和同事的满意度以及下班后放松的能力。由于患有心血管疾病,114名男性被排除在外。在随访期(1985/86 - 1989年),46名男性(约3%)发生了IHD事件,其中11起事件是致命的。与其他人相比,社会阶层最高的人群发生IHD的相对风险及95%置信区间(RR)为0.26(0.06 - 1.09),这种关联无法用主要的潜在混杂因素或效应修饰因素来解释:吸烟、饮酒、身体活动、血压、高血压、体重指数、血清胆固醇、血清甘油三酯、血清高密度脂蛋白以及血清硒。在多变量模型中纳入心理社会因素对估计值影响不大,RR = 0.21(0.05 - 0.95),然而社会阶层之间在心理社会工作条件方面存在高度显著差异。无论是自我报告的对工作的影响力、工作单调性、工作节奏、对直属上级和同事的满意度,还是上述因素的相互作用,均与IHD风险无显著关联。但是,报告称下班后无法放松的男性发生IHD的风险显著增加了约三倍。我们得出结论,在中老年男性中,自我报告的即主观的心理社会工作条件并不能解释IHD方面的社会不平等现象,且自我报告的下班后无法放松与IHD风险增加相关。