Urban E, Pena M
Digestion. 1977;15(1):18-27. doi: 10.1159/000197979.
The influence of luminal lactose and glucose on intestinal calcium transport was examined in vivo in normal post-weaned young rats. In situ segments of duodenum, midgut and ileum were perfused through the lumen for 1 h with an isotonic solution of 3.4 mM calcium containing radioactive isotopic 45Ca as tracer and additionally either 10 mM lactose or 10 mM glucose, or, for the control group, no saccharide. Net absorption was measured by disappearance of luminal calcium; lumen-to-plasma flux was determined from the disappearance of tracer 45Ca. This concentration of luminal lactose or glucose had no direct effect on calcium transport under these steady state conditions.
在正常断奶后的幼鼠体内研究了肠腔乳糖和葡萄糖对肠道钙转运的影响。将十二指肠、中肠和回肠的原位节段通过肠腔用含有放射性同位素45Ca作为示踪剂的3.4 mM钙等渗溶液灌注1小时，另外添加10 mM乳糖或10 mM葡萄糖，或者对于对照组，不添加糖类。通过肠腔钙的消失来测量净吸收；通过示踪剂45Ca的消失来确定肠腔到血浆的通量。在这些稳态条件下，这种肠腔乳糖或葡萄糖浓度对钙转运没有直接影响。
