关于棕榈酸酯被摄取并酯化进入人及大鼠空肠黏膜的体外定量研究。

Quantitative studies in vitro on uptake and esterification of palmitate into human and rat jejunal mucosa.

作者信息

Sueur R, Cerf M, Di Costanzo G, Debray C

出版信息

Digestion. 1977;15(1):34-42. doi: 10.1159/000197981.

DOI:10.1159/000197981

Abstract

Quantitative incorporation and esterification of (9-10) 3H palmitate into jejunal mucosa was studied in vitro comparatively on human biopsies and on everted rings of rat intestine following various incubation times. This procedure is fitted for investigation of the glycophosphate pathway. Quantitatively the total uptake of palmitate was similar in man and rat. But the distribution among the various esterified fractions was different in animal and man and different again in coeliac disease. Notwithstanding incorporation of palmitate into triglyceride the fatty acid composition of mucosal triglyceride showed little or no modification.

摘要

在体外，对人活检组织和大鼠肠外翻环在不同孵育时间后，研究了（9-10）³H 棕榈酸酯在空肠黏膜中的定量掺入和酯化情况。该程序适用于糖磷酸途径的研究。定量而言，人及大鼠中棕榈酸酯的总摄取量相似。但在动物和人之间，以及在乳糜泻患者中，各种酯化组分的分布有所不同。尽管棕榈酸酯掺入了甘油三酯，但黏膜甘油三酯的脂肪酸组成几乎没有变化。