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Plasma corticosterone concentrations in diabetic (db) mice.

作者信息

Coleman D L, Burkart D L

出版信息

Diabetologia. 1977 Jan;13(1):25-6. doi: 10.1007/BF00996323.

DOI:10.1007/BF00996323
PMID:838200
Abstract

Plasma corticosterone concentrations in diabetic (db) mice maintained on two different inbred backgrounds were found to be elevated significantly when compared to normal controls. These data are similar to that reported with the phenotypically similar obese (ob) mouse. These results suggest that the hyperadrenolcorticism is not related to the primary gene action of either gene but rather is a consequence of the development of the obesity-diabetes syndromes.

摘要

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本文引用的文献

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Some aspects of the structure and histochemistry of the adrenals in obese-hyperglycemic mice.
Acta Pathol Microbiol Scand. 1962;54:365-72. doi: 10.1111/j.1699-0463.1962.tb05076.x.
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Expression of gluconeogenic enzymes and 11β-hydroxysteroid dehydrogenase type 1 in liver of diabetic mice after acute exercise.急性运动后糖尿病小鼠肝脏中糖异生酶和 11β-羟类固醇脱氢酶 1 的表达。
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5
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis.瘦素通过抑制下丘脑-垂体-肾上腺轴逆转糖尿病。
Nat Med. 2014 Jul;20(7):759-63. doi: 10.1038/nm.3579. Epub 2014 Jun 15.
6
Downregulation in GATA4 and Downstream Structural and Contractile Genes in the db/db Mouse Heart.db/db小鼠心脏中GATA4及下游结构和收缩基因的下调
ISRN Endocrinol. 2012;2012:736860. doi: 10.5402/2012/736860. Epub 2012 Mar 13.
7
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes.在2型糖尿病患者中,空腹血糖升高与磷酸烯醇式丙酮酸羧激酶(PEPCK)或葡萄糖-6-磷酸酶(G6Pc)表达增加无关。
Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12121-6. doi: 10.1073/pnas.0812547106. Epub 2009 Jul 8.
8
The role of leptin in innate and adaptive immune responses.瘦素在先天性和适应性免疫反应中的作用。
Arthritis Res Ther. 2006;8(5):217. doi: 10.1186/ar2004.
9
Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice.瘦素缺乏小鼠在酵母聚糖诱导的关节炎中急性炎症的延迟消退。
Arthritis Res Ther. 2004;6(3):R256-63. doi: 10.1186/ar1174. Epub 2004 Apr 26.
10
Effect of streptozotocin diabetes and insulin replacement on growth hormone in rats.链脲佐菌素诱导的糖尿病及胰岛素替代对大鼠生长激素的影响。
J Endocrinol Invest. 1985 Feb;8(1):7-11. doi: 10.1007/BF03350625.
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Genetically transmitted obesity in rodents.啮齿动物的遗传性肥胖。
Physiol Rev. 1971 Jul;51(3):598-646. doi: 10.1152/physrev.1971.51.3.598.
6
Studies with the mutation, diabetes, in the mouse.对小鼠糖尿病突变的研究。
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7
The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob-ob mice.
Endocrinology. 1973 Aug;93(2):510-2. doi: 10.1210/endo-93-2-510.
8
The influence of genetic background on the expression of the obese (Ob) gene in the mouse.遗传背景对小鼠肥胖(Ob)基因表达的影响。
Diabetologia. 1973 Aug;9(4):287-93. doi: 10.1007/BF01221856.
9
The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains.遗传背景对小鼠糖尿病位点突变表达的影响。I. C57BL-KsJ和C57BL-6J品系。
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Function of the adrenal cortex in obese-hyperglycemic mice (gene symbol ob).
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