Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line.
作者信息
Tamura K, Tanimoto K, Murakami K, Fukamizu A
机构信息
Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan.
出版信息
Biochim Biophys Acta. 1993 Mar 20;1172(3):306-10. doi: 10.1016/0167-4781(93)90218-3.
PMID:8383538
Abstract
We demonstrated that the mouse renin promoter from -365 to +16 can mediate the activation by cAMP and c-Jun in a kidney-cell dominant manner. Deletion analysis indicated that the region from -75 to -48 was responsible for the activation by cAMP. Furthermore, the core promoter region from -47 to +16 was sufficient to confer c-Jun inducibility.
摘要
Zotero 插件