González Morán M A, Salas Valien J S, Suárez Vilela D, Izquierdo García F M
Servicio de Anatomía Patológica, Complejo Hospitalario de León.
An Med Interna. 1993 Feb;10(2):72-4.
Sigma undifferentiated carcinoma of the rectum is a neuroendocrine tumor embracing less than 1% of all primary malignant epithelial tumors in this location. Recent studies have demonstrated that these tumors are biologically aggressive neoplasias with early metastatic extension. We present one case of loco-regional invasion at the time of the intervention and with distal metastasis within a period of time shorter than one year. We perform a clinical, histological and immunohistochemical study and we comment on the histogenesis of these tumors, their prognosis and treatment, stressing the need of an early diagnosis, an aggressive treatment and an adequate follow-up.
直肠西格玛未分化癌是一种神经内分泌肿瘤，在该部位所有原发性恶性上皮肿瘤中占比不到1%。最近的研究表明，这些肿瘤是具有早期转移扩散的生物学侵袭性肿瘤。我们报告一例在干预时出现局部区域侵犯且在不到一年的时间内发生远处转移的病例。我们进行了临床、组织学和免疫组化研究，并对这些肿瘤的组织发生、预后和治疗进行了评论，强调早期诊断、积极治疗和充分随访的必要性。
