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儿科医生对美国疾病控制中心关于婴儿普遍接种乙肝疫苗的一项新建议的反应。

Reactions of pediatricians to a new Centers for Disease Control recommendation for universal immunization of infants with hepatitis B vaccine.

作者信息

Freed G L, Bordley W C, Clark S J, Konrad T R

机构信息

Division of Community Pediatrics, University of North Carolina, Chapel Hill.

出版信息

Pediatrics. 1993 Apr;91(4):699-702.

PMID:8385309
Abstract

Despite immunization programs targeting high-risk groups, the incidence of hepatitis B has risen 37% over the last decade with 300,000 new infections and 5000 related deaths now occurring annually in the United States. As a new strategy to control the spread of hepatitis B, the Advisory Committee on Immunization Practices of the Centers for Disease Control (CDC) recommended in November 1991 universal hepatitis B immunization of infants. Details were published in an addendum to Morbidity and Mortality Weekly Report. There was no other federal effort to disseminate this recommendation. On February 14, 1992, the American Academy of Pediatrics (AAP) issued a similar recommendation. The time between the CDC and AAP recommendations presented the opportunity to determine the singular effect on clinical practice of the CDC's dissemination effort. The purpose of this study was to assess (1) the effectiveness of the CDC in disseminating a new immunization recommendation, (2) the effect of the new recommendation on clinical practice, and (3) the degree to which noneconomic barriers may affect adoption of universal hepatitis B immunization. All 778 pediatricians in North Carolina were surveyed by mail 2 to 3 months after publication of the new CDC recommendation. Descriptive statistics, chi 2 analysis, and logistic regression were used to assess the relationship of variables hypothesized to predict physician awareness of and/or agreement with the new recommendation. The response rate was 78%. Although 82% of pediatricians who administer immunizations were aware of the new recommendation, only 32% believed it was warranted in their practices.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

尽管针对高危人群开展了免疫计划,但过去十年间美国乙肝发病率仍上升了37%,目前每年有30万新感染病例以及5000例相关死亡。作为控制乙肝传播的一项新策略,疾病控制中心(CDC)免疫实践咨询委员会于1991年11月建议对婴儿进行普遍乙肝免疫接种。详细内容发表在《发病率与死亡率周报》的一份增刊上。没有其他联邦举措来传播这一建议。1992年2月14日,美国儿科学会(AAP)发布了类似建议。CDC和AAP建议发布的时间间隔提供了一个机会,来确定CDC传播努力对临床实践的单一影响。本研究的目的是评估:(1)CDC传播一项新免疫接种建议的有效性;(2)新建议对临床实践的影响;(3)非经济障碍可能影响普遍乙肝免疫接种采用的程度。在CDC新建议发布2至3个月后,通过邮件对北卡罗来纳州的778名儿科医生进行了调查。使用描述性统计、卡方分析和逻辑回归来评估假设变量之间的关系,以预测医生对新建议的知晓和/或认同情况。回复率为78%。尽管82%进行免疫接种的儿科医生知晓新建议,但只有32%认为在他们的实践中该建议是必要的。(摘要截选至250词)

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