Karnovskaia A M
Izv Akad Nauk Ser Biol. 1993 Mar-Apr(2):200-8.
Transport of proteins above 60 kDa into the nuclei involves the nuclear localization signal. The nuclear localization signal of some proteins is considered. Transport of proteins into the nuclei proceeds with the help of the nuclear pore complex. Data on some proteins which possibly fulfill the function of receptors are discussed. Regulation of protein import into the cell nuclei is analyzed by the example of Tetrahymena histone H1, snRNP proteins, etc.
分子量超过60 kDa的蛋白质向细胞核的转运涉及核定位信号。文中考虑了一些蛋白质的核定位信号。蛋白质向细胞核的转运借助核孔复合体进行。讨论了一些可能发挥受体功能的蛋白质的数据。以四膜虫组蛋白H1、小核核糖核蛋白等为例分析了蛋白质向细胞核输入的调控。
