Bloebaum R D, Dupont J A
Bone and Joint Research Labs, VA Medical Center, Salt Lake City, UT 84148.
J Arthroplasty. 1993 Apr;8(2):195-202. doi: 10.1016/s0883-5403(09)80013-2.
The clinical and histological results of hydroxyapatite (HA) coating separation from a press-fit total hip arthroplasty 3.3 years after surgery are documented. Semiquantitative histological analysis showed grade 3+ mononuclear histiocytes and giant cells present in the retrieved capsule and periprosthetic tissues. Grade 3+ (titanium alloy, HA, and polyethylene) particles could be seen throughout the tissues. Backscattered electron and correlated elemental analysis confirmed that the HA coating had migrated to the articulating surface of the polyethylene insert causing third-body wear. The authors suggest that the orthopedic surgeon be cautioned in the routine use of HA-coated implants if osteolysis associated with HA separation and migration is to be avoided.
记录了压配式全髋关节置换术后3.3年羟基磷灰石（HA）涂层分离的临床和组织学结果。半定量组织学分析显示，在取出的关节囊和假体周围组织中存在3+级单核组织细胞和巨细胞。在整个组织中都可以看到3+级（钛合金、HA和聚乙烯）颗粒。背散射电子和相关元素分析证实，HA涂层已迁移到聚乙烯植入物的关节表面，导致三体磨损。作者建议，如果要避免与HA分离和迁移相关的骨溶解，骨科医生在常规使用HA涂层植入物时应谨慎。
