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[肝细胞癌肝切除术的适应证与局限性]

[Indication and limitation of hepatectomy for hepatocellular carcinoma].

作者信息

Kinoshita H, Hirohashi K, Kubo S, Shuto T

机构信息

Second Department of Surgery, Osaka City University Medical School, Japan.

出版信息

Gan To Kagaku Ryoho. 1993 May;20(7):871-6.

PMID:8387757
Abstract

Hepatectomy for hepatocellular carcinoma (HCC) has become safer with recent advances in diagnostic methods, operative techniques and understanding of how to evaluate liver function. Hepatectomy is the treatment of choice for HCC provided that patients are selected carefully, because cure is possible with hepatectomy (some patients survive long without recurrence). However, the rate of recurrence after hepatectomy is high. Recurrences can arise because of either intrahepatic dissemination or factors that give rise to multicentric carcinoma, so one must decide the operative method, to prevent recurrence and the treatment if such occurs, based on the pathogenesis of HCC.

摘要

随着诊断方法、手术技术以及对肝功能评估认识的最新进展,肝细胞癌(HCC)肝切除术已变得更加安全。如果患者经过仔细挑选,肝切除术是HCC的首选治疗方法,因为肝切除术有可能实现治愈(一些患者长期存活且无复发)。然而,肝切除术后的复发率很高。复发可能是由于肝内播散或导致多中心癌的因素引起的,因此必须根据HCC的发病机制来决定手术方法,以预防复发以及复发时的治疗措施。

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