Holtgrave D R, Valdiserri R O, Gerber A R, Hinman A R
National Center for Prevention Services, Centers for Disease Control and Prevention, Atlanta, GA.
Arch Intern Med. 1993 May 24;153(10):1225-30.
The Centers for Disease Control and Prevention (Atlanta, Ga) annually provides more than +100 million in funding to states, territories, and cities for the provision of human immunodeficiency virus (HIV) counseling, testing, referral, and partner notification (CTRPN) services. Given the size of this expenditure, it is important to consider the net benefits of this program activity. We compared the economic costs and benefits of publicly funded HIV CTRPN services.
Standard methods for cost-benefit analysis were used. A societal perspective was employed. Major assumptions used in the base-case analysis included the following: (1) without public funding, the HIV CTRPN services would not be provided; (2) for every 100 HIV-seropositive persons identified and reached by CTRPN services, at least 20 new HIV infections are averted; and (3) for every +100 spent on direct and indirect costs of CTRPN services, approximately another +60 is spent on the ancillary costs of alerting people to HIV issues and CTRPN service availability. Sensitivity analyses were performed to explore the robustness of base-case results to these and other changes in model assumptions.
Under base-case assumptions, the combined direct, indirect, and ancillary costs of the CTRPN program in 1990 dollars were +188,217,600. At a 6% discount rate, the estimated economic benefits of this expenditure are +3,781,918,000. The resultant benefit-cost ratio is 20.09. Sensitivity analyses showed that the benefit-cost ratio is greater than 1 for all considered cases.
This cost-benefit analysis strongly suggests that publicly funded CTRPN services result in a net economic gain to society.
美国疾病控制与预防中心(佐治亚州亚特兰大)每年向各州、领地和城市提供超过1亿美元的资金,用于提供人类免疫缺陷病毒(HIV)咨询、检测、转诊及性伴通知(CTRPN)服务。鉴于此项支出规模,考量该项目活动的净效益十分重要。我们比较了公共资助的HIV CTRPN服务的经济成本与效益。
采用成本效益分析的标准方法。从社会角度进行分析。基础案例分析中使用的主要假设包括:(1)若无公共资金支持,将不会提供HIV CTRPN服务;(2)CTRPN服务每识别并接触到100名HIV血清阳性者,至少可避免20例新的HIV感染;(3)CTRPN服务的直接和间接成本每支出100美元,在提醒人们关注HIV问题及CTRPN服务可及性的辅助成本方面大约还要支出60美元。进行敏感性分析以探究基础案例结果对这些及模型假设中的其他变化的稳健性。
在基础案例假设下,以1990年美元计算,CTRPN项目的直接、间接和辅助成本总计为1.882176亿美元。按6%的贴现率计算,此项支出的估计经济效益为37.81918亿美元。由此得出的效益成本比为20.09。敏感性分析表明,所有考虑的案例中效益成本比均大于1。
此项成本效益分析有力表明,公共资助的CTRPN服务为社会带来了净经济收益。