Bleehen N M, Ford J M
University Department of Clinical Oncology and Radiotherapeutics, Addenbrooke's Hospital, Cambridge, UK.
Curr Opin Oncol. 1993 May;5(3):458-63. doi: 10.1097/00001622-199305000-00004.
This review concentrates on malignant gliomas, with brief mention of cerebral lymphomas, other primary intracranial tumors, and metastases. A recurring theme in the current literature on malignant glioma is the importance of prognostic factors other than treatment in determining outcome. Interesting results are emerging from newer strategies of stereotactic radiotherapy, brachytherapy, and photodynamic therapy, although authors who report these results acknowledge that they have often reviewed patients with intrinsically good prognoses. The year's literature has provided a consolidation of information on prognostic factors, relapse patterns, treatment volume, and dose, providing a basis for future progress.
本综述主要关注恶性胶质瘤，简要提及脑淋巴瘤、其他原发性颅内肿瘤和转移瘤。当前关于恶性胶质瘤的文献中反复出现的一个主题是，除治疗外，预后因素在决定结局方面的重要性。立体定向放射治疗、近距离放射治疗和光动力治疗等新策略正在产生有趣的结果，尽管报告这些结果的作者承认，他们经常回顾那些预后本来就良好的患者。今年的文献对预后因素、复发模式、治疗范围和剂量等信息进行了整合，为未来的进展奠定了基础。
