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[广泛的胃肠道巨细胞病毒感染作为艾滋病的首发表现]

[Widespread gastrointestinal CMV infection as the presenting manifestation of AIDS].

作者信息

Dayan K, Neufeld D M, Lang R, Novis B, Bernheim J, Freund U

机构信息

Dept. of Surgery A, Meir General Hospital.

出版信息

Harefuah. 1993 Feb 1;124(3):124-6, 184.

PMID:8388359
Abstract

A 53-year-old man is reported who developed a widespread gastrointestinal infection due to cytomegalic (CMV) virus and was found to be suffering from AIDS. He died of overwhelming pulmonary infection. There is need for awareness of the rapid increase of AIDS in our local population, particularly in groups not regarded as at high risk. It is imperative to keep this diagnosis in mind when dealing with patients with gastroenterocolitis not responding to standard treatments. CMV has a broad spectrum of clinical manifestations, from carrier state to life-threatening infection. In the gastrointestinal system it causes inflammation and ulcers in the mucosa that may bleed or perforate. There are increasing numbers of reports of CMV ileocolitis in homosexuals with AIDS. The rate of sero-positive CMV in healthy homosexual populations is 94-100% and in 14% there is active infection. CMV is the main infective agent in patients suffering from AIDS; 90% will develop an infection with this virus and in most cases it will be fatal.

摘要

据报道,一名53岁男子因巨细胞(CMV)病毒引发广泛的胃肠道感染,被发现患有艾滋病。他死于严重的肺部感染。有必要认识到艾滋病在我们当地人群中迅速增加的情况,特别是在那些不被视为高危人群的群体中。在处理对标准治疗无反应的胃肠结肠炎患者时,必须牢记这一诊断。CMV具有广泛的临床表现,从携带状态到危及生命的感染。在胃肠道系统中,它会导致黏膜炎症和溃疡,可能会出血或穿孔。艾滋病同性恋者中CMV回肠结肠炎的报告越来越多。健康同性恋人群中CMV血清阳性率为94% - 100%,其中14%存在活动性感染。CMV是艾滋病患者的主要感染病原体;90%的患者会感染这种病毒,且在大多数情况下是致命的。

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1
[Widespread gastrointestinal CMV infection as the presenting manifestation of AIDS].[广泛的胃肠道巨细胞病毒感染作为艾滋病的首发表现]
Harefuah. 1993 Feb 1;124(3):124-6, 184.
2
Frequency of positive tests for cytomegalovirus in AIDS patients: endoscopic lesions compared with normal mucosa.
Am J Gastroenterol. 1993 Mar;88(3):338-43.
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A case of cytomegalovirus enterocolitis diagnosed by the double-balloon enteroscopy.
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[Infection by cytomegalovirus in patients with acquired immunodeficiency syndrome (AIDS): clinical, virological, and histopathological correlations].[获得性免疫缺陷综合征(艾滋病)患者的巨细胞病毒感染:临床、病毒学及组织病理学相关性]
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[Opportunistic infections in AIDS. The pulmonary manifestations].
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[Cytomegalovirus infections in AIDS].
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Laboratory diagnosis of cytomegalovirus (CMV) infections in immunodepressed patients, mainly in patients with AIDS.免疫抑制患者,主要是艾滋病患者巨细胞病毒(CMV)感染的实验室诊断。
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CMV disease in AIDS patients: incidence of CMV disease and relation to survival in a population-based study from Oslo.艾滋病患者的巨细胞病毒疾病:来自奥斯陆的一项基于人群的研究中巨细胞病毒疾病的发病率及其与生存的关系。
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[CMV-associated enterocolitis due to primary CMV infection in the immunocompetent].免疫功能正常者原发性巨细胞病毒感染所致巨细胞病毒相关性小肠结肠炎
Z Gastroenterol. 2013 Nov;51(11):1259-63. doi: 10.1055/s-0031-1273487. Epub 2013 Jan 9.

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