Krishna C M, Roy A K
Solid State & Molecular Physics Division, Saha Institute of Nuclear Physics, Bidhan Nagar, Calcutta.
Indian J Biochem Biophys. 1993 Feb;30(1):7-9.
The photosensitizing properties of p-nitroacetophenone (PNAP), a well-known radiosensitizer, have been studied in near UV region. The mechanism of PNAP photosensitization has been investigated by testing the efficiency of singlet oxygen production using photooxidation of 2,2,6,6-tetramethylpiperidine (TEMP) and photodegradation of guanosine. In both the cases, the enhancement effect of deuterated solvents has been observed. Results of these experiments suggest the significant role of type II mechanisms in PNAP photosensitization.
对硝基苯乙酮(PNAP)是一种著名的放射增敏剂,其光敏特性已在近紫外区域进行了研究。通过测试2,2,6,6 - 四甲基哌啶(TEMP)的光氧化和鸟苷的光降解来研究PNAP光致敏的机制,以检测单线态氧生成的效率。在这两种情况下,均观察到了氘代溶剂的增强作用。这些实验结果表明II型机制在PNAP光致敏过程中起着重要作用。