Pancheva S, Shishkov S, Ilieva D
Institute of Microbiology, Bulgarian Academy of Sciences.
Acta Microbiol Bulg. 1993;29:61-4.
The combination of acyclovir and ribavirin has been established to be more effective on experimental herpes simplex keratoconjunctivitis in rabbits than the treatment with individual drugs. The better therapeutic effect of the combination is proved by the decreased severity of the ocular infection and the reduction of the virus shedding in tear film, as well as by the diminished duration of the infection.
已证实,与单独使用药物治疗相比,阿昔洛韦和利巴韦林联合使用对兔实验性单纯疱疹性角膜结膜炎更有效。联合用药具有更好的治疗效果,这体现在眼部感染严重程度降低、泪膜中病毒脱落减少以及感染持续时间缩短。