Young N, Hollands M, Wong K P
Department of Radiology, Westmead Hospital, Sydney, NSW, Australia.
Australas Radiol. 1993 May;37(2):173-6. doi: 10.1111/j.1440-1673.1993.tb00044.x.
This is a retrospective study to evaluate the ability of arterial chemo-embolization with Adriamycin, Lipiodol and Gelfoam to relieve symptoms, primarily abdominal pain, and to prolong survival in patients with hepatocellular carcinoma. Twenty patients were referred from 1986 to 1991 and in 18 the chemo-embolization procedure was successful. In the follow-up period to March 1992, 17 patients had died. Their survival times were not found to be significantly different from the reported rates of survival in patients given no therapy. In only one of 10 patients followed with computed tomography was a reduction in tumour size seen. Nine of 11 patients with pain reported significant relief from pain following treatment. Six patients had repeat embolizations that successfully relieved recurrent pain. In the authors' experience chemo-embolization was helpful in relieving pain, but did not prolong life.
这是一项回顾性研究，旨在评估阿霉素、碘油和明胶海绵动脉化疗栓塞缓解症状（主要是腹痛）以及延长肝细胞癌患者生存期的能力。1986年至1991年转诊了20例患者，其中18例化疗栓塞手术成功。至1992年3月的随访期内，17例患者死亡。未发现他们的生存时间与未接受治疗患者的报告生存率有显著差异。在接受计算机断层扫描随访的10例患者中，仅1例可见肿瘤大小缩小。报告的11例疼痛患者中有9例在治疗后疼痛明显缓解。6例患者进行了重复栓塞，成功缓解了复发性疼痛。根据作者的经验，化疗栓塞有助于缓解疼痛，但不能延长生命。
