Calonje E, Fletcher C D
Department of Histopathology St. Thomas's Hospital (U.M.D.S.), London, U.K.
Pathologica. 1993 Jan-Feb;85(1095):1-15.
Connective tissue tumours represent a significant group among biopsied skin lesions and manifest a wide range of morphological patterns. While the majority are easily diagnosed, notably most fibrous histiocytomas and neural lesions, a proportion pose considerable diagnostic difficulty. With the increasing recognition and characterisation of previously undescribed entities within the family of soft tissue tumours in recent years, the number of unclassifiable lesions should diminish. The ultimate aim of accurate recognition and classification is to provide appropriate clinical care based on reasoned prediction of a given lesion's behaviour. With this in mind, we wish to briefly review herein some of the more recently characterised dermal connective tissue lesions, including plexiform fibrohistiocytic tumour, cellular fibrous histiocytoma, spindle celled atypical fibroxanthoma, adult myofibroma, dermatomyofibroma, so-called cellular neurothekeoma, ectopic meningothelial hamartoma, tufted angioma, sinusoidal haemangioma and bacillary angiomatosis.
结缔组织肿瘤是活检皮肤病变中的一个重要类别,呈现出广泛的形态学模式。虽然大多数很容易诊断,尤其是大多数纤维组织细胞瘤和神经病变,但有一部分存在相当大的诊断困难。近年来,随着对软组织肿瘤家族中以前未描述的实体的认识和特征描述不断增加,无法分类的病变数量应该会减少。准确识别和分类的最终目的是基于对特定病变行为的合理预测提供适当的临床护理。考虑到这一点,我们在此简要回顾一些最近有特征描述的真皮结缔组织病变,包括丛状纤维组织细胞瘤、细胞性纤维组织细胞瘤、梭形细胞非典型纤维黄色瘤、成人肌纤维瘤、皮肤肌纤维瘤、所谓的细胞性神经鞘瘤、异位脑膜上皮错构瘤、簇状血管瘤、窦状血管瘤和杆菌性血管瘤。