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单次高渗磷酸盐灌肠后出现低钙血症、高磷血症和脱水。

Hypocalcemia, hyperphosphatemia, and dehydration following a single hypertonic phosphate enema.

作者信息

Davis R F, Eichner J M, Bleyer W A, Okamoto G

出版信息

J Pediatr. 1977 Mar;90(3):484-5. doi: 10.1016/s0022-3476(77)80723-3.

DOI:10.1016/s0022-3476(77)80723-3
PMID:839346
Abstract

Previous reports of hypocalcemia and hyperphosphatemia following use of phosphate enemas have either been in patients with renal disease or followed prolonged abuse of these products. The two patients described here had marked elevation of serum phosphate and concomitant lowering of serum calcium secondary to absorption of phosphate from a single administered enema. Associated moderate dehydration resulted in poor renal excretion of the absorbed phosphate and prolongation of hypocalcemia. Hydration was effective in permitting clearance of phosphate and restoration of normocalcemia.

摘要

先前有关使用磷酸盐灌肠剂后出现低钙血症和高磷血症的报道,要么是在患有肾脏疾病的患者中,要么是在长期滥用这些产品之后。此处描述的两名患者因单次使用灌肠剂吸收磷酸盐后,血清磷酸盐显著升高,同时血清钙降低。相关的中度脱水导致肾脏对吸收的磷酸盐排泄不佳,低钙血症持续时间延长。补液有效地促进了磷酸盐的清除并使血钙恢复正常。

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