Hernández A F, Pla A, Valenzuela A, Gil F, Villanueva E
Department of Legal Medicine, Faculty of Medicine, University Hospital, University of Granada, Spain.
Chem Biol Interact. 1993 Jun;87(1-3):173-7. doi: 10.1016/0009-2797(93)90039-2.
In this study, the presence of paraoxonase activity in pericardial fluid was demonstrated. A comparison of some properties, such as optimum pH, stability versus pH, heat inactivation, effect of inhibitors, isoelectric point and kinetic parameters (Km and Vmax), between plasma and pericardial fluid paraoxonase was made. The properties studied were practically identical. The enzyme activity in pericardial fluid was tested as a marker in the postmortem diagnosis of myocardial infarction. The paraoxonase activity in the myocardial infarction group (47 cases) was lower than in the control group (40 cases), but the difference was not significant.
在本研究中，证实了心包液中存在对氧磷酶活性。对血浆和心包液对氧磷酶的一些特性进行了比较，如最适pH值、pH稳定性、热失活、抑制剂的作用、等电点和动力学参数（Km和Vmax）。所研究的特性实际上是相同的。测试了心包液中的酶活性作为心肌梗死死后诊断的标志物。心肌梗死组（47例）的对氧磷酶活性低于对照组（40例），但差异不显著。
