Lansky L L, Kalavsky S M, Brackett C E, Wallas C H, Reis R L
J Pediatr. 1977 Apr;90(4):639-40. doi: 10.1016/s0022-3476(77)80390-9.
The number of children in this report treated with either TBW or exchange transfusions is small. Case mortality rates among children with Reye syndrome in Stage IV coma tends to be exceedingly high, varying from 50 to 100%. Intracranial pressure monitoring with the subarachnoid screw may have been an additional factor in increasing our survival data in three patients in the TBW group, since it provided continuous monitoring of ICP and allowed judicious administration of mannitol intravenously. Survival of five of six patients without neurologic sequelae in the present series has encouraged us to coninue utilization of TBW in children with Stage IV Reye syndrome.
本报告中接受全血交换输血（TBW）或换血治疗的儿童数量较少。处于IV期昏迷的瑞氏综合征患儿的病死率往往极高，在50%至100%之间。蛛网膜下腔螺钉颅内压监测可能是提高我们TBW组3例患者生存数据的另一个因素，因为它能持续监测颅内压，并允许谨慎静脉注射甘露醇。本系列中6例患者中有5例无神经后遗症存活，这鼓励我们继续对IV期瑞氏综合征患儿使用全血交换输血。
