Alkaline phosphatase, arylsulfatase and beta-glucuronidase in saliva of cyclic women.

Levels of the enzymes alkaline phosphatase, arylsulfatase, and beta-glucuronidase have been measured in whole unstimulated saliva samples collected daily during normal menstrual cycles. The cellular content of the saliva has been shown to be a major source of the three enzymes. The enzymes were found to have peak maximum levels of activity during the periovulatory -hase of the cycle. This observation can be attributed to the presence of increased numbers of exfoliated cells from the oral mucosa resulting from the pre-ovulatory estrogen stimulus to cell proliferation.