Halawa B
Katedry i Kliniki Kardiologii AM, Wrocławiu.
Pol Tyg Lek. 1993;48(3-4):77-9.
Density of beta-adrenergic receptors in the lymphocytes, alpha 1- and alpha 2-adrenergic receptors in blood platelets, as well as blood serum norepinephrine levels have been assessed in 49 patients with congestive heart failure prior to, and 7 and 14 days of captopril and lisinopril administration. A decrease in beta-, alpha 1-, and alpha 2-adrenergic receptors density, an increase in blood serum norepinephrine, and normal epinephrine levels have been noted in these patients. A 7-day treatment with captopril, and a 14-day treatment with lisinopril have increased adrenergic receptors density, and decreased blood serum norepinephrine levels.
对49例充血性心力衰竭患者在服用卡托普利和赖诺普利之前以及用药7天和14天后，评估了淋巴细胞中β-肾上腺素能受体的密度、血小板中α1-和α2-肾上腺素能受体的密度以及血清去甲肾上腺素水平。这些患者出现β-、α1-和α2-肾上腺素能受体密度降低、血清去甲肾上腺素升高以及肾上腺素水平正常的情况。卡托普利7天的治疗以及赖诺普利14天的治疗使肾上腺素能受体密度增加，血清去甲肾上腺素水平降低。
