人类肿瘤中的RNA:DNA比率。

RNA:DNA ratios in human tumors.

作者信息

Kravetz de Srulijes L, Israeli E, Barzilai D

出版信息

J Natl Cancer Inst. 1977 Mar;58(3):769-70. doi: 10.1093/jnci/58.3.769.

DOI:10.1093/jnci/58.3.769

Abstract

A study has been made of the quantitative relation existing between the RNA:DNA ratios in benign and in malignant human tumors. It has been demonstrated that a significant difference (Student's t-test) existed between malignant and benign human tumors within the different groups studied: a) malignant and benign breast tumors (t=2.22, P less than 0.05); b) Hodgkin's disease in spleen and its controls (t=2.39, P less than 0.02); and c) malignant and benign thyroid tumors (t=4.23, P less than 0.01). The diagnostic value of this finding is discussed.

摘要

一项关于人类良性肿瘤与恶性肿瘤中RNA:DNA比率之间定量关系的研究已经完成。研究表明，在所研究的不同组中，人类恶性肿瘤与良性肿瘤之间存在显著差异（采用学生t检验）：a）恶性与良性乳腺肿瘤（t = 2.22，P < 0.05）；b）脾脏中的霍奇金病及其对照（t = 2.39，P < 0.02）；以及c）恶性与良性甲状腺肿瘤（t = 4.23，P < 0.01）。本文讨论了这一发现的诊断价值。