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[周围神经损伤——当前治疗标准]

[Peripheral nerve injuries--current treatment standard].

作者信息

Penkert G

机构信息

Neurochirurgische Klinik, Krankenhaus Nordstadt Hannover.

出版信息

Zentralbl Neurochir. 1993;54(2):47-51.

PMID:8396291
Abstract

A review of our century's efforts to overcome nerve defects reveals the conclusion that today microsurgical techniques and interfascicular nerve grafting offer the best chances to get success in peripheral nerve repair. There exists a theoretical grading system of Sunderland, which enables us to understand the very different factors which might influence the sprouting of nerve fibers within the damaged or repaired nerve segments. But in practice, the indication to operate always depends on our own decision. The neurological status and electrophysiological tests can only sometimes facilitate our treatment and judgement on peripheral nerve lesions. The basic principles of microsurgical nerve repair are still valid. Modern techniques have resulted in better prognosis. Vast mobilization to achieve neurorrhaphy by force is obsolete today. Epineural trunk-to-trunk-suture is only allowed after clean cut-injuries. In all other cases we have to prefer a repair by autologous grafting. But some factors still remain which limits our efforts, such as muscle degeneration depending on time interval or ischemic fibrosis after the lesion, direct trauma to the muscle substance or a lesion in the region of nerve ramifications.

摘要

回顾我们这个世纪为克服神经缺损所做的努力,可以得出这样的结论:如今,显微外科技术和束间神经移植为周围神经修复取得成功提供了最佳机会。存在一种理论上的桑德兰分级系统,它使我们能够理解可能影响受损或修复神经段内神经纤维发芽的各种不同因素。但在实际操作中,手术指征始终取决于我们自己的决定。神经学状态和电生理测试有时只能辅助我们对周围神经损伤的治疗和判断。显微外科神经修复的基本原则仍然有效。现代技术带来了更好的预后。如今,通过强行广泛游离来实现神经缝合的做法已过时。只有在锐器切割伤后才允许进行神经干对神经干的外膜缝合。在所有其他情况下,我们必须优先选择自体移植修复。但仍有一些因素限制着我们的努力,比如取决于时间间隔的肌肉变性、损伤后的缺血性纤维化、对肌肉实质的直接创伤或神经分支区域的损伤。

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