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[疱疹感染局部和全身形式中胸腺受累的特征]

[The characteristics of thymus involvement in regional and generalized forms of herpetic infection].

作者信息

Kolomiets A G, Duboĭskaia G P, Gasich E L, Kolomiets N D, Votiakov V I

出版信息

Biull Eksp Biol Med. 1993 Jun;115(6):649-52.

PMID:8397019
Abstract

The features of thymus involvement in pathologic process in different types of experimental herpetic infection in rabbits were studied using morphologic and immunologic analysis methods. Insignificant features of thymus pathology were revealed in animals with regional manifestations of the infection in the form of ophthalmoherpes, whereas the rabbits with generalized herpes simplex virus (HSV) infection by retrosternal administration showed pronounced structural-functional changes and the presence of virus antigens as well, which may indicate the possibility of HSV reproduction in thymus cells.

摘要

采用形态学和免疫学分析方法,研究了不同类型实验性兔疱疹感染病理过程中胸腺受累的特征。在以眼疱疹形式出现感染局部表现的动物中,胸腺病理表现不明显;而通过胸骨后给药感染单纯疱疹病毒(HSV)的全身性感染的兔子,则表现出明显的结构功能变化,且存在病毒抗原,这可能表明HSV在胸腺细胞中具有复制的可能性。

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