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[一例胃癌伴多发肝转移对表柔比星/丝裂霉素C-碘油混悬液动脉内灌注有显著反应的病例]

[A case of gastric cancer with multiple liver metastases responding significantly to intra-arterial infusion of epirubicin/mitomycin C-lipiodol suspension].

作者信息

Sato Y, Kono H, Minami K, Yamamoto T, Nagata N

机构信息

Dept. of Surgery, Hiroshima Prefectural Akitsu Hospital.

出版信息

Gan To Kagaku Ryoho. 1993 Sep;20(12):1857-60.

PMID:8397490
Abstract

We encountered a case of partial response in a patient with multiple liver metastases from gastric cancer as a result of treatment by hepatic artery infusions of epirubicin/mitomycin C-Lipiodol suspension. A 56-year-old man was diagnosed as having advanced gastric cancer with multiple liver metastases. Subtotal gastrectomy with regional lymph node dissection and cholecystectomy were performed, and an injection port was implanted in the proper hepatic artery. Ten days after the operation, the intermittent chemotherapies were performed, and 3 months after the effect was judged to be a partial response by CT scan. Severe side effects were not seen during treatment, and the man is now healthy and working for more than one year after the operation. Thus, this regimen may be found useful for patients with liver metastases.

摘要

我们遇到一例胃癌多发肝转移患者,通过肝动脉输注表柔比星/丝裂霉素C-碘油混悬液治疗后出现部分缓解。一名56岁男性被诊断为晚期胃癌伴多发肝转移。行胃大部切除术加区域淋巴结清扫及胆囊切除术,并在肝固有动脉植入注射端口。术后10天开始进行间歇性化疗,3个月后CT扫描判断疗效为部分缓解。治疗期间未出现严重副作用,该男子术后至今健康并已工作一年多。因此,这种治疗方案可能对肝转移患者有用。

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