Kazui H, Tanabe H, Nakagawa Y, Ikeda M, Ikejiri Y, Shiraishi J, Hirano S, Kato A, Yoshimine T, Hayakawa T
Faculty of Health and Sport Sciences, Osaka University, Toyonaka, Japan.
No To Shinkei. 1993 Jul;45(7):641-8.
In 3 patients with brain tumors involving language areas, we investigated functional cortical regions and epileptogenic foci using subdural electrode stimulation before operation. These stimulation studies were useful in preserving postoperatively their language function. The following neuropsychological findings were obtained; (1) Stimulation of Broca area (Brodmann 44 and 45) did not produce anarthria (phonetic disintegration), but semantic and phonemic parahasias and word finding difficulties. (2) Stimulation of lower motor cortex elicited anarthria. (3) Buccofacial apraxia was not produced only by stimulation of frontal operculum. (4) When anarthria was elicited by stimulation, difficulty in retrieving both Kana and Kanji letter-forms and paragraphia in Kana letters were sometimes observed. (5) Stimulation at Exner's writing centre did not produce writing deficits, but elicited word finding difficulties and paraphasias.
在3例涉及语言区域的脑肿瘤患者中,我们在术前使用硬膜下电极刺激研究了功能皮质区域和致痫灶。这些刺激研究有助于术后保留他们的语言功能。获得了以下神经心理学发现:(1)刺激布罗卡区(布罗德曼44区和45区)不会导致构音障碍(语音解体),但会出现语义和音素性错语以及找词困难。(2)刺激初级运动皮层会引发构音障碍。(3)仅刺激额盖不会产生口面部失用症。(4)当刺激引发构音障碍时,有时会观察到假名和汉字字母形式检索困难以及假名书写障碍。(5)刺激埃克斯纳书写中枢不会导致书写缺陷,但会引发找词困难和错语。