Harris J P, Kreipe R E, Rossbach C N
Department of Pediatrics, University of Rochester Medical Center, New York 14642.
J Adolesc Health. 1993 Jul;14(5):390-3. doi: 10.1016/s1054-139x(08)80013-4.
A 17-year-old male with anorexia nervosa developed atypical prolongation of his corrected QT interval (QTc) when placed on isoproterenol for profound sinus bradycardia. His QTc normalized after the infusion was discontinued. Autonomic imbalance may explain the observed QTc lengthening. Because bradycardia associated with weight loss in anorexia is usually a physiologic adaptation and rarely symptomatic, aggressive chronotropic therapy may be not only unwarranted, but potentially deleterious.
一名17岁神经性厌食症男性患者，因严重窦性心动过缓使用异丙肾上腺素后出现校正QT间期（QTc）非典型延长。输注停止后其QTc恢复正常。自主神经失衡可能是观察到的QTc延长的原因。由于厌食症中与体重减轻相关的心动过缓通常是一种生理适应且很少有症状，积极的变时性治疗不仅可能不必要，而且可能有害。
