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[硫氧还蛋白还原酶:结构、性质及功能]

[Thioredoxin-reductase: structure, properties, and function].

作者信息

Labudova O, Kollarova M

出版信息

Biokhimiia. 1993 Aug;58(8):1240-6.

PMID:8399772
Abstract

Thioredoxin reductase (TR-RED) pertains to the family of pyridine nucleotide disulfide oxidoreductases distinguished by their remarkable structural homology. The enzyme is a constituent component of the thioredoxin complex which is present in all types of organisms and is universal in respect of the numerous physiological functions it performs. The ability of TR-RED to protect the skin from UV-generated free oxygen species has been found. Owing to its ability to control melanin biosynthesis, the enzyme "doses" the suntan.

摘要

硫氧还蛋白还原酶(TR-RED)属于吡啶核苷酸二硫化物氧化还原酶家族,其显著的结构同源性使其独具特色。该酶是硫氧还蛋白复合体的组成成分,存在于所有类型的生物体中,并且因其执行的众多生理功能而具有普遍性。已发现TR-RED具有保护皮肤免受紫外线产生的游离氧物种伤害的能力。由于其能够控制黑色素的生物合成,这种酶可调节晒黑程度。

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