Maslov A G, Lychev V G, Maslova G N
Biull Eksp Biol Med. 1993 Jul;116(7):23-5.
The effect of direct electric current (DEC), 0.4 mA, on the ultrastructure of normal perfusing isolated heart and in the course of its postischemic reperfusion was studied on the model of isolated rat heart using Langedorf method. DEC was shown to exert a normalizing, membrane-stabilizing effect on the subcellular organization of isolated heart CMC in the course of its normothermic perfusion. The observed changes are considered to attest to the adaptive aspect of the current effect on the ultrastructure of the myocardium under these conditions. In ischemia-reperfusion, DEC also facilitated marked stabilization of cardiomyocytes membranes and stimulation of intracellular reparative processes of the affected cardiac muscle.
采用Langendorff法，以离体大鼠心脏为模型，研究了0.4 mA直流电（DEC）对正常灌注离体心脏超微结构及其缺血后再灌注过程的影响。结果表明，在常温灌注过程中，DEC对离体心脏CMC的亚细胞组织具有正常化、膜稳定作用。观察到的变化被认为证明了在这些条件下电流对心肌超微结构影响的适应性方面。在缺血-再灌注过程中，DEC还促进了心肌细胞膜的显著稳定，并刺激了受影响心肌的细胞内修复过程。
