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[大鼠感觉运动皮层V层锥体神经元在缺血后时期的树突可塑性]

[The dendritic plasticity of the pyramidal neurons in layer V of the rat sensorimotor cortex in the postischemic period].

作者信息

Akulinin V A, Semchenko V V, Belichenko P V

出版信息

Biull Eksp Biol Med. 1993 Jul;116(7):94-6.

PMID:8400199
Abstract

Dendrites plasticity of pyramidal neurons in layer V of rat sensomotor cortex was analyzed during postischemic period. Oblique dendrites and their spines of pyramidal neurons were more reactive for ischemia after 1 day aa manifested by decrease in their length, branching, the volume of dendritic territory and number of dendritic spines. This testifies to high sensitivity to the ischemic influence of stimulating aditus of pyramidal neurons of layer V in the sensomotor cortex of rat. At 7 days of postischemic damage, dendrites of pyramidal neurone were mostly reduced. The quantitative parameters of dendritic geometry recovered after 30 and 90 days of ischemia.

摘要

在缺血后时期分析了大鼠感觉运动皮层V层锥体神经元的树突可塑性。锥体神经元的斜向树突及其棘在缺血1天后对缺血反应更强,表现为其长度、分支、树突区域体积和树突棘数量减少。这证明大鼠感觉运动皮层V层锥体神经元的刺激入口对缺血影响高度敏感。在缺血损伤7天时,锥体神经元的树突大多减少。缺血30天和90天后,树突几何形状的定量参数恢复。

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