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健脾金丹对正常及环磷酰胺诱导免疫抑制小鼠免疫功能的增强作用

[Enhancing effect of jian pi jin dan on immune functions of normal and cyclophosphamide induced immunosuppressed mice].

作者信息

Fan Y P

机构信息

Beijing College of TCM.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 Apr;13(4):223-5, 198.

PMID:8400772
Abstract

UNLABELLED

By means of normal and cyclophosphamide (CY) injected NIH mice, the effect of Jian Pi Jin Dan on immuno-modulation was studied which could treat the "Gan" disease effectively in TCM.

RESULTS

Markedly improved the level of serum lysozyme, enhance the phagocytosis of abdominal macrophage. The proliferation of spleen T, B cells, the production of interleukin-1 (IL-1) by macrophage and of interleukin-2 (IL-2) by T cells in normal and CY injected mice were also enhanced. Furthermore, it was able to restore the weight, spleen and thymus index of CY injected mice. This prescription can not only reinforce Spleen, but also regulate Liver, complying to the children's physiological and pathological characteristics.

摘要

未标记

通过对正常和注射环磷酰胺(CY)的 NIH 小鼠,研究健脾金丹对免疫调节的作用,该药在中医中能有效治疗“肝”病。

结果

显著提高血清溶菌酶水平,增强腹腔巨噬细胞的吞噬作用。正常和注射 CY 的小鼠脾脏 T、B 细胞的增殖,巨噬细胞产生白细胞介素 -1(IL -1)以及 T 细胞产生白细胞介素 -2(IL -2)也得到增强。此外,它能够恢复注射 CY 小鼠的体重、脾脏和胸腺指数。该方剂不仅能健脾,还能疏肝,符合儿童的生理和病理特点。

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