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胰岛素依赖型糖尿病患者因过量注射胰岛素企图自杀。

Attempted suicide by insulin overdose in insulin-requiring diabetics.

作者信息

Martin F I, Hansen N, Warne G L

出版信息

Med J Aust. 1977 Jan 15;1(3):58-60. doi: 10.5694/j.1326-5377.1977.tb130503.x.

DOI:10.5694/j.1326-5377.1977.tb130503.x
PMID:840089
Abstract

Four cases of suicidal insulin overdose in insulin-requiring diabetics presented to one hospital in three years. In three cases there was a history of depression; but despite huge doses of insulin (3,000 and 1,500 units) in two, no patient died and only one had residual signs of clinical brain damage. The estimated plasma insulin level was not well correlated with the severity of the hypoglycaemia. It is probable that suicidal insulin overdose is more common than reports in the literature suggest, and may often be unrecognized. The dissociation between huge doses of insulin and the severity of the subsequent hypoglycaemia in diabetics is unexplained.

摘要

三年内,一家医院收治了4例需要胰岛素治疗的糖尿病患者自杀性过量注射胰岛素的病例。其中3例有抑郁症病史;尽管有2例注射了大剂量胰岛素(3000单位和1500单位),但没有患者死亡,只有1例有临床脑损伤的残留体征。估计的血浆胰岛素水平与低血糖的严重程度相关性不佳。自杀性过量注射胰岛素可能比文献报道的更为常见,而且可能常常未被识别。糖尿病患者大剂量胰岛素与随后低血糖严重程度之间的分离现象尚无法解释。

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Attempted suicide by insulin overdose in insulin-requiring diabetics.胰岛素依赖型糖尿病患者因过量注射胰岛素企图自杀。
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Intentional overdose with insulin: prognostic factors and toxicokinetic/toxicodynamic profiles.胰岛素故意过量使用:预后因素及毒代动力学/毒效学特征
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