Boiron J M, Ellie E, Vital A, Lagueny A, Vital C, Julien J, Reiffers J
Unité de Greffe de Moëlle, Hopital Haut-Lévêque, Pessac, France.
Leuk Lymphoma. 1993 Aug;10(6):489-91. doi: 10.3109/10428199309148207.
We report a 30 year old patient with acute lymphoblastic leukemia (ALL) whose leukemic relapse presented as an isolated symmetrical peripheral neuropathy with facial diplegia. Initially, this was consistent with a Guillain-Barré syndrome but the peripheral nerve biopsy revealed leukaemic infiltration. This was followed by a systemic relapse. Reports of peripheral nerve infiltration are scarce and to the best of our knowledge this is the first documented case of peripheral polyneuropathy as a presenting manifestation of ALL relapse.
我们报告了一名30岁的急性淋巴细胞白血病（ALL）患者，其白血病复发表现为孤立性对称性周围神经病变伴双侧面瘫。最初，这与吉兰 - 巴雷综合征相符，但周围神经活检显示有白血病浸润。随后出现了全身复发。周围神经浸润的报告很少，据我们所知，这是第一例记录在案的以周围性多发性神经病作为ALL复发首发表现的病例。
