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[哮喘患者用力肺活量相关参数分析及奈多罗米钠治疗效果]

[Analysis of selected spirometric parameters and results of therapy with nedocromil sodium in patients with asthma].

作者信息

Rutkowski R, Siergiejko Z, Chyrek-Borowska S

机构信息

Kliniki Alergologii AM, Białymstoku.

出版信息

Pneumonol Alergol Pol. 1993;61(7-8):377-82.

PMID:8401344
Abstract

The effect of 12 weeks therapy with nedocromil sodium given as MDI-aerosol, 8 mg/daily in a group of 20 atopic asthmatic patients was studied. The selected spirometric parameters (PEF, FEV1, FVC, FEF25-75%, Raw) and clinical symptoms of bronchial asthma (dyspnoea, cough, sputum) were assessed. Additionally the percentage reduction of bronchodilators usage was obtained. A significant improvement was observed in spirometric parameters. A statistically significant reduction in clinical symptoms of bronchial asthma and bronchodilators usage was noted.

摘要

研究了20名特应性哮喘患者组成的一组每日吸入8毫克奈多罗米钠定量气雾剂进行为期12周治疗的效果。评估了选定的肺功能参数(呼气峰流速、第一秒用力呼气容积、用力肺活量、25%-75%用力呼气流量、气道阻力)和支气管哮喘的临床症状(呼吸困难、咳嗽、咳痰)。此外,还得出了支气管扩张剂使用量减少的百分比。观察到肺功能参数有显著改善。注意到支气管哮喘的临床症状和支气管扩张剂使用量有统计学意义的降低。

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