Ikegami F, Sakai R, Ishikawa T, Kuo Y H, Lambein F, Murakoshi I
Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Biol Pharm Bull. 1993 Jul;16(7):732-4. doi: 10.1248/bpb.16.732.
2-(3-Amino-3-carboxypropyl)-isoxazolin-5-one (ACI), a neurotoxic amino acid from Lathyrus odoratus, was confirmed to be derived enzymatically from S-adenosyl-L-methionine (SAM) and isoxazolin-5-one. Some properties of an enzyme in the biosynthesis of ACI are described.