Makovskaia V A, Kudriashov Iu A, Tkachenko B I
Fiziol Zh Im I M Sechenova. 1993 Jul;79(7):82-90.
Under conditions of perfusion of the small intestine's vessels with constant volume of the auto-blood, stationary shifts of the arterial perfusion pressure by +/- 50 mm Hg and/or blood flow by +/- 50% of the initial level practically did not affect the size of the exchange surface of the organ's microvessel bed (the capillary filtration coefficient) or the average capillary pressure in artificially stabilised pressure of venous outflow at the level of 6 mm Hg. However, under conditions of normo-, hypo- and hypertone of the small vessels' smooth muscles, the shifts of the venous outflow pressure (from 0 to 24 mm Hg) increased the exchange surface of the microvessels and the average capillary pressure. The mechanisms of the shifts in microhemodynamics and transcapillary exchange of fluid are discussed.
在以恒定体积的自身血液灌注小肠血管的条件下,动脉灌注压在初始水平基础上稳定变化±50 mmHg和/或血流量稳定变化±50%,实际上并未影响器官微血管床的交换面积(毛细血管滤过系数),也未影响在人为稳定的静脉流出压为6 mmHg水平时的平均毛细血管压。然而,在小血管平滑肌处于正常、低张和高张状态的条件下,静脉流出压的变化(从0至24 mmHg)会增加微血管的交换面积和平均毛细血管压。文中讨论了微循环动力学变化及液体跨毛细血管交换的机制。