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[血流变化以及动脉压和静脉压水平对小肠滤过-吸收过程的影响]

[The effect of changes in the blood flow and the level of arterial and venous pressures on the filtration-absorptive processes in the small intestine].

作者信息

Makovskaia V A, Kudriashov Iu A, Tkachenko B I

出版信息

Fiziol Zh Im I M Sechenova. 1993 Jul;79(7):82-90.

PMID:8401675
Abstract

Under conditions of perfusion of the small intestine's vessels with constant volume of the auto-blood, stationary shifts of the arterial perfusion pressure by +/- 50 mm Hg and/or blood flow by +/- 50% of the initial level practically did not affect the size of the exchange surface of the organ's microvessel bed (the capillary filtration coefficient) or the average capillary pressure in artificially stabilised pressure of venous outflow at the level of 6 mm Hg. However, under conditions of normo-, hypo- and hypertone of the small vessels' smooth muscles, the shifts of the venous outflow pressure (from 0 to 24 mm Hg) increased the exchange surface of the microvessels and the average capillary pressure. The mechanisms of the shifts in microhemodynamics and transcapillary exchange of fluid are discussed.

摘要

在以恒定体积的自身血液灌注小肠血管的条件下,动脉灌注压在初始水平基础上稳定变化±50 mmHg和/或血流量稳定变化±50%,实际上并未影响器官微血管床的交换面积(毛细血管滤过系数),也未影响在人为稳定的静脉流出压为6 mmHg水平时的平均毛细血管压。然而,在小血管平滑肌处于正常、低张和高张状态的条件下,静脉流出压的变化(从0至24 mmHg)会增加微血管的交换面积和平均毛细血管压。文中讨论了微循环动力学变化及液体跨毛细血管交换的机制。

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