de Blasio F, Daughton D M, Thompson A B, Robbins R A, Spurzem J R, Sisson J H, Von Essen S G, Romberger D J, Rubinstein I, Floreani A A
Second Medical School, Naples University, Italy.
Chest. 1993 Oct;104(4):1032-7. doi: 10.1378/chest.104.4.1032.
Bronchoalveolar lavage (BAL) can be performed with the patient undergoing either local or general anesthesia (GA). This study investigates whether the type of anesthesia affects BAL fluid and cell recovery. Eighty patients, were selected for study. Fluid recoveries were significantly less in the GA group for both the bronchial and alveolar lavages. The differences were confirmed for BAL fluid recovery in a subsequent group of 120 unselected patients. Bronchoscope size did not appear to affect recovery, nor did anesthesia time; BAL fluid recovery from patients with respiratory failure who were intubated and mechanically ventilated was similar to that in the GA group, suggesting that lower recovery rates may be due to mechanical ventilation. The BAL fluid cell counts were related to fluid recovery, but airway neutrophils represented a higher percentage of BAL lavage fluid cells in the GA lavages, independent of differences in the volume of lavage fluid recovered.
支气管肺泡灌洗（BAL）可在患者接受局部麻醉或全身麻醉（GA）的情况下进行。本研究调查麻醉类型是否会影响BAL液和细胞回收。选取了80例患者进行研究。全身麻醉组在支气管灌洗和肺泡灌洗中的液体回收量均显著减少。在随后一组120例未经筛选的患者中，BAL液回收量的差异得到了证实。支气管镜尺寸似乎不影响回收量，麻醉时间也不影响；插管并机械通气的呼吸衰竭患者的BAL液回收量与全身麻醉组相似，这表明回收率较低可能是由于机械通气所致。BAL液细胞计数与液体回收量有关，但在全身麻醉灌洗中，气道中性粒细胞在BAL灌洗液细胞中所占百分比更高，与回收的灌洗液量差异无关。
