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生物膜在屈指肌腱修复中预防粘连应用的实验研究

[Experimental study on the application of biological membrane to prevent adhesions in the flexor tendon repair].

作者信息

Shao X Z

机构信息

Third Hospital of Hebei Medical College.

出版信息

Zhonghua Wai Ke Za Zhi. 1993 Jan;31(1):56-9.

PMID:8404347
Abstract

UNLABELLED

Flexor digitorum profundus of adult Leghorn hens was used in the experiment.

CONTROL GROUP

the long flexor tendons were cut and sutured with sheath excised between A2 and A4. Experimental group: the biological membrane was placed circumferentially around the repair site to reconstruct the flexor sheath after flexor tendon repair. The tendon healing, the adhesions and the development of pseudosheath were examined by naked eyes, optical and electron microscopy respectively. It was proved that the membrane not only could separate the healing flexor tendon from the surrounding tissue and reduce adhesion, but did not cause any local and systemic adverse reaction. The results showed that the development of the new tendon sheaths around the biological membrane was similar to silastic prosthesis in morphology. The pseudosynovial sheath supplied good tissue bed for tendon gliding. It was found that the stimulation of the membrane to the surrounding tissue was the basis of new sheath formation in the early stage and tendon gliding in the late stage would promote the pseudosheath to be mature and stable. Therefore, the results provided experimental basis for clinical practice.

摘要

未标记

实验采用成年来亨鸡的指深屈肌。

对照组

切断长屈肌腱并在A2和A4之间切除腱鞘后进行缝合。实验组:在屈肌腱修复后,将生物膜环绕修复部位放置以重建屈肌腱鞘。分别通过肉眼、光学显微镜和电子显微镜检查肌腱愈合情况、粘连情况以及假腱鞘的形成情况。结果证明,该生物膜不仅能将愈合中的屈肌腱与周围组织分隔开并减少粘连,而且不会引起任何局部和全身不良反应。结果显示,生物膜周围新腱鞘的形成在形态上与硅橡胶假体相似。假滑膜腱鞘为肌腱滑动提供了良好的组织床。研究发现,生物膜对周围组织的刺激是早期新腱鞘形成的基础,而后期的肌腱滑动会促使假腱鞘成熟和稳定。因此,该结果为临床实践提供了实验依据。

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