胰岛素依赖型糖尿病（IDDM）和非胰岛素依赖型糖尿病（NIDDM）患者胰腺的超声检查异常情况。

Ultrasonographic abnormalities of the pancreas in IDDM and NIDDM patients.

作者信息

Silva M E, Vezozzo D P, Ursich M J, Rocha D M, Cerri G G, Wajchenberg B L

机构信息

Endocrine Service, University of Sao Paulo Medical School, Brazil.

出版信息

Diabetes Care. 1993 Sep;16(9):1296-7. doi: 10.2337/diacare.16.9.1296.

DOI:10.2337/diacare.16.9.1296

PMID:8404436

Abstract

OBJECTIVE

To evaluate the relationship between the type and duration of diabetes and pancreas size by ultrasonography.

RESEARCH DESIGN AND METHODS

Pancreas images of 40 IDDM and 36 NIDDM patients with 0.3-34 yr of disease were compared with those of 60 normal healthy control subjects.

RESULTS

The diameters +/- SD of the head, body, and tail of the pancreas in IDDM patients (1.9 +/- 0.3; 0.9 +/- 0.2; and 1.4 +/- 0.2 cm, respectively) were smaller than in NIDDM patients (2.7 +/- 0.4; 1.2 +/- 0.3; and 1.8 +/- 0.4 cm, respectively) and control group subjects (2.4 +/- 0.4; 1.1 +/- 0.3; and 1.8 +/- 0.4 cm, respectively). The pancreatic shrinkage in IDDM patients was clearly evident after 10 yr of the disease. NIDDM patients and control subjects had similar pancreatic dimensions, except for a greater body thickness in NIDDM patients with > 10 yr of disease (1.2 +/- 0.4 vs. 1.1 +/- 0.3 cm). These results were not related to differences in age, sex, and body size. Pancreas image was hypoechogenic in 72.5% of IDDM patients and hyperechogenic in 83.3% of NIDDM patients.

CONCLUSIONS

Smaller pancreases in IDDM patients in comparison with NIDDM patients and control subjects were clearly demonstrated only after 10 yr of disease. Patients with NIDDM were not affected by pancreatic dimensions, except for a greater body thickness after 10 yr of disease. Pancreatic echogenicity increased with age.

摘要