Haude M, Issa H, Herber M, Meyer J, Erbel R
Abteilung für Kardiologie, Universität Essen.
Dtsch Med Wochenschr. 1993 Sep 24;118(38):1349-54. doi: 10.1055/s-2008-1059460.
Restenosis rate after successful intracoronary implantation of Palmaz-Schatz stents in 100 patients (92 men, 8 women; mean age 57 +/- 11 years) was quantitatively assessed by angiography performed on average 5.3 +/- 0.3 months after the procedure. Restenosis was defined as a more than 50% decrease in lumen. Data from patients with acute or subacute thrombotic complications were excluded from the analysis. The restenosis rate of the total group was 22%. After placement of only one stent (n = 87) it was 17%, of multiple stents per lesion (n = 13) 54%. Restenosis rate after emergency implantation of a single stent (n = 23) was 17.4%, after elective single stent implantation (n = 64) 17.2%. There was no significant difference regarding treatment of new stenoses (n = 16), and recurrent stenosis (n = 48), namely 12.5% vs 18.8%. The following were risk factors for chronic restenosis after stent implantation: multiple stents (odds ratio [OR] 5.6; 95% confidence interval [CI]: 1.6-19.1); implantation in a small vessel, reference diameter < or = 3.0 mm (OR 6.7, CI 2.4-18.7); and residual stenosis after stent implantation of > 8% (OR 3.1, CI 1.2-8.1).
对100例患者（92例男性，8例女性；平均年龄57±11岁）成功进行冠状动脉内Palmaz-Schatz支架植入术后，平均在术后5.3±0.3个月通过血管造影对再狭窄率进行定量评估。再狭窄定义为管腔缩小超过50%。分析中排除了有急性或亚急性血栓并发症患者的数据。整个组的再狭窄率为22%。仅植入一枚支架（n = 87）后的再狭窄率为17%，每个病变植入多枚支架（n = 13）后的再狭窄率为54%。紧急植入单枚支架（n = 23）后的再狭窄率为17.4%，择期植入单枚支架（n = 64）后的再狭窄率为17.2%。新狭窄（n = 16）和复发性狭窄（n = 48）的治疗方面无显著差异，分别为12.5%对18.8%。支架植入后慢性再狭窄的危险因素如下：多枚支架（优势比[OR] 5.6；95%置信区间[CI]：1.6 - 19.1）；植入小血管，参考直径≤3.0 mm（OR 6.7，CI 2.4 - 18.7）；支架植入后残余狭窄＞8%（OR 3.1，CI 1.2 - 8.1）。
