肛周乳腺外佩吉特病。两例报告。
Perianal extramammary Paget's disease. Report of two cases.
作者信息
Herzog U, von Flüe M, de Roche R, Curschellas E
机构信息
Surgical Departement St. Claraspital, Basel, Switzerland.
出版信息
Eur J Surg Oncol. 1993 Oct;19(5):469-73.
Perianal (extramammary) Paget's disease is rare and corresponds to an intraepithelial adenocarcinoma arising from dermal apocrine sweat glands. Biopsy reveals the diagnosis. The condition is often associated with an underlying malignancy (carcinoma of the apocrine or eccrine glands, rectal carcinoma, anal carcinoma). Wide local excision is recommended when invasive growth is absent. For invasive cancer or when associated with a synchronous malignancy abdomino-perineal resection is the treatment of choice. Two cases of perianal Paget's disease are presented.
肛周（乳腺外）佩吉特病罕见，是一种起源于真皮大汗腺的上皮内腺癌。活检可明确诊断。该病常与潜在恶性肿瘤（大汗腺或小汗腺癌、直肠癌、肛管癌）相关。无浸润性生长时，建议行广泛局部切除。对于浸润性癌或伴有同步恶性肿瘤时，腹会阴联合切除术是首选治疗方法。本文介绍两例肛周佩吉特病病例。
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