Smurzynski J, Jung M D, Lafreniere D, Kim D O, Kamath M V, Rowe J C, Holman M C, Leonard G
Department of Surgery, University of Connecticut Health Center, Farmington.
Ear Hear. 1993 Aug;14(4):258-74. doi: 10.1097/00003446-199308000-00005.
Full-term and preterm infants were evaluated with click-evoked and distortion-product otoacoustic emissions (CEOEs and DPOEs). The CEOEs and DPOEs recorded from each individual ear were analyzed by calculating the root-mean-square levels within half-octave bands. The fail criterion of the OE tests was that the half-octave RMS DPOE or CEOE levels of an ear under test were below the 10th percentile of full-term newborns in two or more bands. The DPOE data were collected from 118 ears of 61 premature babies; 80 (68%) ears passed the DPOE test, 30 (25%) ears without middle ear effusions failed the test, and 8 (7%) ears with effusions also failed. The CEOE data were collected from 128 ears of 65 premature babies; 102 (80%) ears passed the CEOE test, 18 (14%) ears without middle ear effusions failed the test, and 8 (6%) ears with effusions also failed. In 23 of 80 ears (29%) that passed the DPOE test and in 23 of 102 ears (23%) that passed the CEOE test, RMS OE levels of preterm infants were above the 90th percentile of full-term newborns. The analyses of the combined DPOE and CEOE data obtained from a group of 25 ears of full-term newborns and from a group of 72 ears of preterm babies showed statistically significant correlations between the DPOE and CEOE root-mean-square levels in each of the half-octave bands in the 1.4 to 4 kHz region. For 42 preterm infants tested with auditory brain stem response (ABR), specificity was 86% for CEOE and 74% for DPOE. All infants who failed the ABR also failed OE tests. To the best of our knowledge, this study is the first using combined DPOEs, CEOEs, and ABRs for preterm babies. It showed the feasibility of DPOEs and CEOEs for this population.
对足月儿和早产儿进行了瞬态诱发耳声发射（CEOEs）和畸变产物耳声发射（DPOEs）评估。通过计算半倍频程带内的均方根水平，对从每个耳朵记录到的CEOEs和DPOEs进行分析。耳声发射测试的失败标准是，受试耳朵的半倍频程均方根DPOE或CEOE水平在两个或更多频段低于足月儿的第10百分位数。从61名早产儿的118只耳朵收集了DPOE数据；80只（68%）耳朵通过了DPOE测试，30只（25%）无中耳积液的耳朵测试失败，8只（7%）有积液的耳朵也测试失败。从65名早产儿的128只耳朵收集了CEOE数据；102只（80%）耳朵通过了CEOE测试，18只（14%）无中耳积液的耳朵测试失败，8只（6%）有积液的耳朵也测试失败。在通过DPOE测试的80只耳朵中的23只（29%）以及通过CEOE测试的102只耳朵中的23只（23%）中，早产儿的耳声发射均方根水平高于足月儿的第90百分位数。对从一组25只足月儿耳朵和一组72只早产儿耳朵获得的DPOE和CEOE组合数据进行分析，结果显示在1.4至4 kHz区域的每个半倍频程带中，DPOE和CEOE均方根水平之间存在统计学显著相关性。对42名接受听性脑干反应（ABR）测试的早产儿而言，CEOE的特异性为86%，DPOE的特异性为74%。所有ABR测试失败的婴儿耳声发射测试也失败。据我们所知，本研究是首次对早产儿联合使用DPOEs、CEOEs和ABRs。它显示了DPOEs和CEOEs在该人群中的可行性。
